Secondary Structure Search

Enter an RNA sequence with or without dot/bracket notation for comparison to the R-BIND library

Enter RNA Sequence Input:
Example: GACGAAAACGUC

Enter Dot-Bracket Structure (optional):
Example: ((((....))))

Upon entering an RNA sequence of interest, the algorithm will conduct a minimum free energy prediction of its secondary structure and identify elements such as bulges, internal loops, and apical loops. If the dot-bracket notation is provided, the search will be conducted based on the given structure rather than the minimum free energy prediction. It will then compare these structures to those found in the R-BIND database looking for identical RNA elements (not-sequence based) and output the ligands that bind those targets.